bumps and lumps on your vagina and vulva can be normal, or they could be a sign of a condition that requires medical attention. Female genital sores are bumps and lesions in or around the vagina. Some sores may be itchy, painful, or produce a discharge, while others may not cause any symptoms. This is one of the most common bump-related reasons women wind up in dwecks office. If you look at the opening of the vagina like its a clock with the clitoris. a swollen bump near the opening of your vagina may also be a bartholin gland cyst. The bartholin glands release fluid during sex that helps with lubrication. Vaginal cysts can become infected by the normal bacteria found on the skin or by a sexually transmitted infection. Infected vaginal cysts can form an abscess -- a pus-filled lump that can be very. a lump or bump on the vagina may have a variety of causes. Causes can include cysts, warts, polyps, and, rarely, vaginal cancer. if the weird bump or lump is near the opening to your vagina, it may be a bartholins cyst, says allison hill, md, an ob-gyn at good samaritan hospital. Hello, i wanted to ask you a question regarding a bump that has appeared between my leg and vagina. I am in my ealry twenties, am sexually active but always have protected sex with only one partner, and havent shaved recently. I have had bumps before there that appeared to be more or less like cysts, a bump would appear, it would hurt and then would either burst and puss and a bit of blood. Started off with a painful bump end the center of my purbic hair line that just out of know were started burning and then it just capt growing as days gone buy. Out of know where i would jump because it burned so bad like menistrail cramps. On the thired week i decided to put preprationh on it and it caused it to ooz a small pin whole of vocanno pus that is.